WNT5A Antibody, ALEXA FLUOR 350

  • Catalog number
    bs-1948R-A350
  • Price
    Please ask
  • Size
    100ul
  • Long name
    WNT5A Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-WNT5A PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    WNT5A
  • Specificity
    This is a highly specific antibody against WNT5A.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    330-380/381
  • Subcellular location
    Secreted
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WNT5A
  • Gene ID Number
    7474
  • Swiss Prot
    P41221
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat, Dog
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    hWNT5A; Protein Wnt-5a; WNT5A
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 350
  • French translation
    anticorps
  • Gene target
    WNT5A  
  • Gene symbol
    WNT5A, WNT5A-AS1
  • Short name
    Anti-WNT5A
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 350
  • Alternative name
    WNT5A Polyclonal Antibody, ALEXA FLUOR 350
  • Alternative technique
    antibodies
  • Alternative to gene target
    wingless-type MMTV integration site family, member 5A, hWNT5A, WNT5A and IDBG-40713 and ENSG00000114251 and 7474, receptor a this GO nist activity, Extracellular, Wnt5a and IDBG-141666 and ENSMUSG00000021994 and 22418, BT.88484 and IDBG-645372 and ENSBTAG00000020221 and 530005
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    WNT5A antisense RNA 1
  • Synonyms gene name
    • WNT5A antisense RNA 1 (non-protein coding)
  • Locus
  • Discovery year
    2011-07-25
  • Classification
    • Antisense RNAs
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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