Lithocholic acid

• Catalog number
  2187-1G
• Price
  Please ask
• Size
  1 g

• Alternative_name
  3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol; LCA
• Description
  Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-α dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 binding sites of both MDM2 and MDM4 with a five-fold preference for MDM4.
• CAS Number
  434-13-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₄₀O₃
• Molecular Weight
  376.57
• Cell Permeable
  No
• Purity
  ≥97% by TLC
• Solubilities
  DMSO or EtOH
• Handling
  Protect from air and moisture
• Tag Line
  A detergent and an endogenous inhibitor of MDM2 and MDM4
• Storage Condition
  RT
• Shipping Condition
  RT
• Shelf Life
  24months
• MDL Number
  MFCD00003682
• PubChem CID
  9903
• PubChem CID Link
• SMILES
  CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
• InChi
  InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
• InChi Key
  SMEROWZSTRWXGI-HVATVPOCSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Lithocholic   acid  
• Short name
  Lithocholic acid
• Alternative name
  Lithocholic acid

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