IgE, Heavy Chain (Biotin)

• Catalog number
  GEN633284
• Price
  Please ask
• Size
  500ug

• Also known as
  IgE, Heavy Chain
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  3H2284
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Mouse (Mus musculus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes the mouse epsilon immunoglobulin heavy chain and does not crossreact with other mouse immunoglobulin classes or subclasses.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at -20 degrees Celsius.
• Tested applications
  ELISA (EL/EIA)
• Properties
  Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Conjugation
  Biotinylated

• Gene target
  Heavy   Chain  
• Gene symbol
  CLTC, MYH13, FTHL18P
• Short name
  IgE, Heavy Chain ( )
• Technique
  IgE, IgEs
• Isotype
  IgE, IgE
• Label
  Biotin
• Alternative name
  Anti-IgE, Heavy Chain (Biotin)
• Alternative technique
  immunoglobulin-e

Gene info

• Identity
  HGNC:2092
• Gene
  CLTC
• Long gene name
  clathrin heavy chain
• Synonyms gene
  • CLTCL2
• Synonyms gene name
  • clathrin, heavy polypeptide (Hc)
  • clathrin, heavy chain
  • clathrin, heavy polypeptide-like 2
  • clathrin, heavy chain (Hc)
• Synonyms
  • Hc
• GenBank acession
  • X55878
• Locus
  17q23.1
• Discovery year
  1990-10-16
• Entrez gene record
  1213
• Pubmed identfication
  • 1765375
  • 7584026
• RefSeq identity
  • NM_004859
• Classification
  • Clathrin subunits
• VEGA ID
  OTTHUMG00000134279

Gene info

• Identity
  HGNC:7571
• Gene
  MYH13
• Long gene name
  myosin heavy chain 13
• Synonyms gene name
  • myosin, heavy polypeptide 13, skeletal muscle
• Synonyms
  • MyHC-eo
• Synonyms name
  • extraocular muscle myosin heavy chain
  • extraocular myosin heavy chain
• GenBank acession
  • AF075248
• Locus
  17p13.1
• Discovery year
  1998-12-09
• Entrez gene record
  8735
• Pubmed identfication
  • 9806854
• RefSeq identity
  • NM_003802
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000177987

Gene info

• Identity
  HGNC:3988
• Gene
  FTHL18P
• Long gene name
  ferritin heavy chain like 18, pseudogene
• Synonyms gene
  • FTH1P18
  • FTHL18
• Synonyms gene name
  • ferritin, heavy polypeptide-like 18
  • ferritin, heavy polypeptide 1 pseudogene 18
  • ferritin heavy chain 1 pseudogene 18
  • ferritin heavy chain like 18
• GenBank acession
  • AA383232
• Locus
  Xp21.1
• Discovery year
  2000-05-31
• Entrez gene record
  441490
• RefSeq identity
  • NR_171164
• VEGA ID
  OTTHUMG00000033090

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