GM2A Antibody, ALEXA FLUOR 488

• Catalog number
  bs-13452R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  GM2A Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-GM2A PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GM2A
• Specificity
  This is a highly specific antibody against GM2A.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  160-193/193
• Subcellular location
  Lysosome
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GM2A/SAP3
• Gene ID Number
  2760
• Swiss Prot
  P17900
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  SAP-3; GM2-AP; Ganglioside GM2 activator; Cerebroside sulfate activator protein; Sphingolipid activator protein 3; GM2A
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-GM2A has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  GM2A  
• Gene symbol
  GM2A
• Short name
  Anti-GM2A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  GM2A Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4367
• Gene
  GM2A
• Long gene name
  GM2 ganglioside activator
• Synonyms gene name
  • GM2 ganglioside activator protein
• Synonyms
  • SAP-3
• Synonyms name
  • cerebroside sulfate activator protein
  • sphingolipid activator protein 3
• Locus
  5q33.1
• Discovery year
  1986-01-01
• Entrez gene record
  2760
• Pubmed identfication
  • 115863
  • 1915857
• RefSeq identity
  • NM_000405
• VEGA ID
  OTTHUMG00000130124
• Locus Specific Databases
  • GM2A Locus Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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