anti-UEV1A Antibody

• Catalog number
  3375
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  UEV1A Antibody: Ubiquitin-conjugating enzyme E2 (UEV1) was initially discovered as a protein similar in sequence and structure to the E2 ubiquitin-conjugating enzymes but lacking their enzymatic activity. There are at least two variants and multiple isoforms of UEV1. In particular, UEV1A (Ubiquitin-conjugating enzyme E2 variant 1 isoform A) has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway. Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors. UEV1A is part of a dimeric ubiquitin-conjugating enzyme complex also containing Ubc13 (ubiquitin-conjugating enzyme 13) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family. The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation.
• Gene names
  UEV1A Antibody: CIR1, UEV1, CROC1, UBE2V, UEV-1, UEV1A, CROC-1, P/OKcl.19, Ubiquitin-conjugating enzyme E2 variant 1
• Antibodie s label
  unlabelled serum
• Purity
  UEV1A Antibody is Ion exchange chromatography purified.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Anti-UEV1A may also recognize other isoforms of UEV1A.
• Antigen
  UEV1A antibody was made against a peptide corresponding to 15 amino acids near the C-terminus of human UEV1A.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  UEV1A antibody can be used for detection of UEV1A by Western blot at 1 to 4 ug/mL.
• Suspention pH azide
  UEV1A Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  UEV1A antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  40806167
• Ncbi nr
  NP_954595
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  7335
• GENE symbol
  UBE2V1
• Antigene name
  ubiquitin-conjugating enzyme E2 variant 1
• Source
  Homo sapiens
• Protein nr
  Q13404
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  UEV1A  
• Gene symbol
  UBE2V1
• Short name
  anti-UEV1A Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toUEV1A (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12494
• Gene
  UBE2V1
• Long gene name
  ubiquitin conjugating enzyme E2 V1
• Synonyms gene
  • UBE2V
• Synonyms gene name
  • ubiquitin-conjugating enzyme E2 variant 1
• Synonyms
  • UEV-1
  • CROC-1
  • UEV1A
  • CROC1
• GenBank acession
  • U39360
• Locus
  20q13.13
• Discovery year
  1998-03-20
• Entrez gene record
  7335
• Pubmed identfication
  • 9418904
  • 9305758
• RefSeq identity
  • NM_021988
• Classification
  • Ubiquitin conjugating enzymes E2
• VEGA ID
  OTTHUMG00000152626

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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