GITRL, Soluble, Recombinant, Mouse (His) (Glucocorticoid-induced TNF Receptor Ligand, AITRL, Activation-inducible TNF-related Ligand, TNFSF18)

  • Catalog number
    MBS637149
  • Price
    Please ask
  • Size
    0,05 mg
  • Other size
    please contact us to order other different size
  • Conjugation
    histidine
  • Description
    Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene
    Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
  • Gene target
    GITRL   Soluble   His   Glucocorticoid   TNF   Receptor   Ligand   AITRL   Activation   TNF-related   Ligand   TNFSF18  
  • Gene symbol
    TNF, TNFRSF1A, TNFRSF1B, TNFSF18, LTBR
  • Short name
    GITRL, Soluble, Recombinant, Mouse (His) (Glucocorticoid- TNF Receptor Ligand, AITRL, Activation- TNF- Ligand, TNFSF18)
  • Technique
    Recombinant, activation, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Host
    mouse
  • Label
    His
  • Species
    Mouse, Mouses
  • Alternative name
    GITRL, Soluble, Rec., Mouse (histidine) (Glucocorticoid-induced tumor necrosis factor Receptor Ligand, AITRL, Activation-inducible tumor necrosis factor-related Ligand, tumor necrosis factor (ligand) superfamily, member 18)
  • Alternative technique
    rec, murine
  • Alternative to gene target
    tumor necrosis factor (ligand) superfamily, member 18, AITRL and GITRL and hGITRL and TL6, TNFSF18 and IDBG-104861 and ENSG00000120337 and 8995, tumor necrosis factor receptor superfamily binding, Extracellular, Tnfsf18 and IDBG-201543 and ENSMUSG00000066755 and 240873, LOC768081 and IDBG-632315 and ENSBTAG00000047412 and 768081
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
    Primary Cell Culture
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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GITRL Soluble Recombinant Mouse His) (Glucocorticoid TNF Rec
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