Deprenyl, Apoptosis Inhibitor

• Catalog number
  SIH-209-1G
• Price
  Please ask
• Size
  1 g

• Stock availabilitIn Stock
  In Stock
• CAS number
  14611-52-0
• Description
  Apoptosis Inhibitor
• Molecular weight
  223,74 g/mol
• Primary research fields
  Cancer, Apoptosis
• Other name
  N-Methyl-N-[(2R)-1-phenyl-2-propanyl]-2-propyn-1-amine, Selegiline
• Product category
  Small Molecules
• Product type
  Inhibitor
• Chemical formula
  C13H17N·HCl
• Origin
  Synthetic
• Purity pourcentage
  >99%
• Soluble in
  Soluble to 100 mM in water, and to 100 mM in ethanol
• Physical appearance
  White Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility
• PubChem number
  26757
• Scientific context
  Deprenyl or Selegiline is a drug used for the treatment of early stage Parkinson’s (1), depression and senile dementia (2). It is a selective irreversable inhibitor of monoamine oxidase B (MAO-b).
• Bibliography
  1. Lachenmayer L., and Laux G. (2004) Curr Med Chem. 11(15): 2033-2043. 2. FDA US Food and Drug Administration. Press Announcements Feb 28, 2006. www.fda.gov/newsevents/newsroom/pressannouncements/2006/ucm108607.htm
• Release date
  8-Apr-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of Deprenyl (SIH-209), a glyceraldehyde-3-phosphate dehydrogenase inhibitor. CAS #: 14611-52-0. Molecular Formula: C13H17N · HCl . Molecular Weight: 223.74 g/mol. Chemical structure of Deprenyl, a glyceraldehyde-3-phosphate dehydrogenase inhibitor (SIH-209). CAS # 14611-52-0. Molecular Formula: C13H17N · HCl .
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  1
• Other related products
• Additional description
  This 1 is suited for programmed cell-death studies. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Deprenyl   Inhibitor  
• Short name
  Deprenyl, Apoptosis Inhibitor
• Technique
  apoptosis, apoptosis pathway
• Alternative name
  Deprenyl, programmed cellular destruction suppressor
• Alternative technique
  celldeath

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