Recombinant Rat CD23 / FCER2 / FCER2A Protein (Fc tag) 100µg
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Catalog number
PKSR030317-100µg
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Price
Please ask
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Size
100µg
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Synonym
FCER2;Fcer2a
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Activity
NA
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Sequence
Glu50-Pro331
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Fusion tag
N-Fc
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Accession
Q6AZ45
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ExpressedHost
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 90 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
60.2 kDa
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AP Mol Mass
61 KDa
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Formulation
Lyophilized from sterile PBS, PH 7.4
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Background
Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor).
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FCER2
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Short name
Recombinant CD23 / FCER2 / FCER2A Protein (Fc tag) 100µg
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Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
Rat
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Label
Fc Tag
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Species
Rat, Rats
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Alternative name
Rec. Rat CD23 / fragment c fragment on immunoglobuline E, low affinity II, receptor to measure (CD23) / FCER2A Protein (fragment c detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
Fc fragment of IgE, low affinity II, receptor for (CD23), BLAST-2 and CD23 and CD23A and CLEC4J and FCE2 and IGEBF, FCER2 and IDBG-23316 and ENSG00000104921 and 2208, metal ion binding, Cell surfaces, Fcer2a and IDBG-130417 and ENSMUSG00000005540 and 14128, FCER2 and IDBG-643690 and ENSBTAG00000004270 and 407106
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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