SU-5614

  • Catalog number
    9643-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    (3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one; GK4754
  • Description
    SU-5614 is a potent and selective FLT3 (FMS-like tyrosine kinase 3) inhibitor. SU5614 has inhibitory activity for FLT3 and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
  • CAS Number
    1055412-47-9
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₁₃ClN₂O
  • Molecular Weight
    272.73
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>20 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective FLT3  inhibitor.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD08443928
  • PubChem CID
    6536806
  • SMILES
    CC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C
  • InChi
    InChI=1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-
  • InChi Key
    XLBQNZICMYZIQT-GHXNOFRVSA-N
  • MSDS Available
    Yes
  • Gene target
    SU-5614  
  • Short name
    SU-5614
  • Alternative name
    SU-5614
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