SU-5614
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Catalog number9643-25
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PricePlease ask
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Size25 mg
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Alternative_name(3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one; GK4754
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DescriptionSU-5614 is a potent and selective FLT3 (FMS-like tyrosine kinase 3) inhibitor. SU5614 has inhibitory activity for FLT3 and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
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CAS Number1055412-47-9
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₁₃ClN₂O
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Molecular Weight272.73
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>20 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent and selective FLT3 inhibitor.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD08443928
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PubChem CID6536806
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SMILESCC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C
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InChiInChI=1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-
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InChi KeyXLBQNZICMYZIQT-GHXNOFRVSA-N
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MSDS AvailableYes
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Gene target
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Short nameSU-5614
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Alternative nameSU-5614
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