CD59 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-1638R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  CD59 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-CD59 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CD59
• Specificity
  This is a highly specific antibody against CD59.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  70-90/128
• Subcellular location
  Helical
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD59
• Gene ID Number
  966
• Swiss Prot
  P13987
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  1F5; EJ16; EJ3; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF2; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-2; MAC-IP; p18-2; CD59 glycoprotein; 1F5 antigen; 2 kDa homologous restriction factor; MAC-inhibitory protein; MEM43 antigen; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; Protectin; CD59
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-CD59 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  CD59  
• Gene symbol
  CD59
• Short name
  Anti-CD59
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  CD59 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  CD59 molecule, complement regulatory protein, 16.3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 and IDBG-38813 and ENSG00000085063 and 966, protein binding, Extracellular, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574

Gene info

• Identity
  HGNC:1689
• Gene
  CD59
• Long gene name
  CD59 molecule (CD59 blood group)
• Synonyms gene
  • MIC11
  • MIN1
  • MSK21
  • MIN2
  • MIN3
• Synonyms gene name
  • CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
  • CD59 antigen, complement regulatory protein
  • CD59 molecule, complement regulatory protein
  • CD59 molecule
• Synonyms
  • 16.3A5
  • EJ16
  • EJ30
  • EL32
  • G344
  • p18-20
• Locus
  11p13
• Discovery year
  1989-06-30
• Entrez gene record
  966
• Pubmed identfication
  • 7691713
  • 27187193
• RefSeq identity
  • NM_203329
• Classification
  • Blood group antigens
  • Complement system regulators and receptors
  • CD molecules
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000166270
• Locus Specific Databases
  • CD59base: Mutation registry for CD59 deficiency
  • LRG_41

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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