TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207) Antibody
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Catalog numberMBS611884
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PricePlease ask
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Size100ug
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Alternative name1Anti-TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)
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Alternative name2TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)
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Alternative name3TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)
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Alternative name4TWEAK
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Alternative name5Anti -TWEAK (TNF-related Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207)
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Other namestumor necrosis factor ligand superfamily member 12 proprotein; Tumor necrosis factor ligand superfamily member 12; tumor necrosis factor ligand superfamily member 12; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; tumor necrosis factor (ligand) superfamily, member 12; APO3 ligand; TNF-related weak inducer of apoptosis
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesTNFSF12; TNFSF12; APO3L; DR3LG; TWEAK; APO3L; DR3LG; TWEAK
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismHost: Rabbit; Source: Human
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Species reactivityHuman, Mouse
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Specificity and cross reactivityRecognizes human TWEAK. Species Crossreactivity: mouse
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Purification methodAffinity Purified by immunoaffinity chromatography.
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Form AppearanceSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested forWestern Blot (WB)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional descriptionThis 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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French translationanticorps
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Gene target
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Gene symbolTNFSF12, TNF, TNFRSF1A, TNFRSF1B, LTBR, TNFSF12-TNFSF13, TNFRSF12A, TNFRSF25
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Short nameTWEAK (TNF- Weak Inducer of Apoptosis, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand Superfamily Member 12, TNFSF12, UNQ181/PRO207) Antibody
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Techniqueapoptosis, Antibody, antibodies against human proteins, antibodies for, apoptosis pathway
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Alternative nameTWEAK (tumor necrosis factor-related Weak Inducer on programmed cellular destruction, APO3 Ligand, APO3/DR3 Ligand, APO3L, CD255, DR3LG, FN14, HCG1991317, MGC129581, MGC20669, Tumor Necrosis Factor Ligand supergroup Member 12, tumor necrosis factor (ligand) superfamily, member 12, UNQ181/PRO207) (antibody to-)
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Alternative techniquecelldeath, antibodies
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Alternative to gene targettumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 12
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 12
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNFSF12-TNFSF13 readthrough
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-07-31
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 12A
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 12A
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-20
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 25
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
- tumor necrosis factor receptor superfamily, member 25
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data