Paromomycin Sulfate

Alternative_name

Aminosidin sulfate; Gabbroral; Aminoxidin; Farmiglucin; Humagel; Humatin; Pargonyl; Sinosid; D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1- >4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)- beta-D-ribofuranosyl-(1->5))-2-deoxy-, sulfate (salt
Description

Paromomycin Sulfate is an aminoglycoside antibiotic that inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
CAS Number

1263-89-4
Structure Available

Yes
Molecular Formula

C₂₃H₄₅N₅O₁₄·H₂SO₄
Molecular Weight

713.71
Cell Permeable

Yes
Purity

POTENCY: ≥65 IU/mg
Solubilities

H₂O (~50 mg/ml)
Handling

Protect from air and moisture
Tag Line

An aminoglycoside antibiotic and protein synthesis inhibitor
Storage Condition

+4°C
Shipping Condition

Gel Pack
Shelf Life

36 months
MDL Number

MFCD00079278
PubChem CID

441375
PubChem CID Link
SMILES

C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O
InChi

InChI=1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
InChi Key

LJRDOKAZOAKLDU-UDXJMMFXSA-N
Data Sheet Link
MSDS Available

Yes