8-Hydroxy-2'-deoxyguanosine
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Catalog number2177-1
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PricePlease ask
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Size1 mg
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Alternative_name8-Oxo-dG; 8-Oxo-7,8-dihydrodeoxyguanosine; 8-Hydroxydeoxyguanosine; 7,8-Dihydro-8-oxo-2’-deoxyguanosine; sine; 8-OH-dG
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Description8-Hydroxy-2-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a critical biomarker of oxidative stress and carcinogenesis.
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CAS Number88847-89-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₀H₁₃N₅O₅
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Molecular Weight283.24
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~ 12 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA critical biomarker of oxidative stress and carcinogenesis
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD00210311
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PubChem CID73318
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SMILESC1C(C(OC1N2C3=C(C(=O)N=C(N3)N)NC2=O)CO)O
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InChiInChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1
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InChi KeyHCAJQHYUCKICQH-VPENINKCSA-N
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MSDS AvailableYes
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Gene target
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Short name8-Hydroxy-2'-deoxyguanosine
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Alternative name8-Hydroxy-2'-deoxyguanosine
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