Rat Anti-Mouse CD44/Pgp-1-PE

• Catalog number
  GEN673105
• Price
  Please ask
• Size
  100ug

• Also known as
  CD44/Pgp-1
• Other names
  CD44 antigen; CD44 protein; CD44 antigen; PGP-1; PGP-I; HUTCH-I; ECMR-III; hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; phagocytic glycoprotein I; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; Cell surface glycoprotein CD44 (hyaluronate binding protein); Cd44 molecule; N/A
• Category
  Secondary Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Cd44; Cd44; CD44A; METAA; RHAMM; MGC124941; CD44
• Gene name synonims
  Cd44; Cd44; CD44A; METAA; RHAMM; MGC124941; CD44
• Other gene names
  Cd44; Cd44; CD44A; METAA; RHAMM; MGC124941; CD44
• Clonality
  Monoclonal
• Immunoglobulin isotype
  Rat IgG1 kappa
• Clone
  KM201
• Host organism
  Rat (Rattus norvegicus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  All isoforms of CD44/pgp-1 (Mr 80-95 kDa) CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock- Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD^4+ T cells.^1-6; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  R - phycoerythrin (R - PE) Conjugate
• Concentration
  N/A
• Storage and shipping
  The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS, pH 7.4, containing 0.1% sodium azide as preservative and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below Store the antibody at -20 degrees Celsius.. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product the antibody should be stored at -20 degrees Celsius. immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Tested applications
  Flow Cytometry; Immunoprecipitation; Western Blot
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

• Gene target
  CD44/Pgp-1-PE  
• Gene symbol
  ETV3, ERF, CD44-AS1, CD44, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
• Short name
  Anti-Mouse CD44/Pgp-1-PE
• Technique
  anti-, Mouse, anti, antibody to, antibodies, mouses
• Host
  Rat
• Label
  PE
• Species
  Mouse, Mouses, Rats
• Alternative name
  Anti-Rat Anti-Mouse CD44/Pgp-1-PE
• Alternative technique
  murine, antibodies
• Alternative to gene target
  CD44 molecule (Indian blood group), CDW44 and CSPG8 and ECMR-III and HCELL and HUTCH-I and IN and LHR and MC56 and MDU2 and MDU3 and MIC4 and Pgp1, CD44 and IDBG-39556 and ENSG00000026508 and 960, hyaluronic acid binding, Cell surfaces, Cd44 and IDBG-193505 and ENSMUSG00000005087 and 12505, CD44 and IDBG-636564 and ENSBTAG00000011578 and 281057

Gene info

• Identity
  HGNC:3492
• Gene
  ETV3
• Long gene name
  ETS variant transcription factor 3
• Synonyms gene name
  • ets variant gene 3, ETS family transcriptional repressor
  • ETS variant 3
• Synonyms
  • PE-1
• GenBank acession
  • BC022868
• Locus
  1q23.1
• Discovery year
  1994-12-15
• Entrez gene record
  2117
• Pubmed identfication
  • 8020980
• RefSeq identity
  • NM_005240
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000034298

Gene info

• Identity
  HGNC:3444
• Gene
  ERF
• Long gene name
  ETS2 repressor factor
• Synonyms gene name
  • Ets2 repressor factor
• Synonyms
  • PE-2
  • PE2
• GenBank acession
  • U58535
• Locus
  19q13.2
• Discovery year
  1998-07-17
• Entrez gene record
  2077
• Pubmed identfication
  • 7588608
  • 9192842
• RefSeq identity
  • NM_006494
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000182788

Gene info

• Identity
  HGNC:40133
• Gene
  CD44-AS1
• Long gene name
  CD44 antisense RNA 1
• Synonyms
  • RP1-68D18.4
• Locus
  11p13
• Discovery year
  2017-02-10
• Pubmed identfication
  • 28103885
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:1681
• Gene
  CD44
• Long gene name
  CD44 molecule (Indian blood group)
• Synonyms gene
  • MIC4
  • MDU2
  • MDU3
• Synonyms gene name
  • CD44 antigen (homing function and Indian blood group system)
• Synonyms
  • IN
  • MC56
  • Pgp1
  • CD44R
  • HCELL
  • CSPG8
• Synonyms name
  • hematopoietic cell E- and L-selectin ligand
  • chondroitin sulfate proteoglycan 8
• GenBank acession
  • M59040
• Locus
  11p13
• Discovery year
  1989-06-30
• Entrez gene record
  960
• Pubmed identfication
  • 2454887
• RefSeq identity
  • NM_000610
• Classification
  • Proteoglycans
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000044388
• Locus Specific Databases
  • LRG_815

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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