Rabbit anti Cysteine string protein (CSP) Alpha antibody DNAJC5 alpha

• Catalog number
  X2406P
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings. The amino terminus of CSP contains the J domain, a consensus sequence found on a DnaJ like protein which is a member of the heatshock protein family. Since heat shock proteins serve as chaperones that participate in protein folding and protein complex formation, CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. Evidence for a role of CSP in presynaptic neurotransmitter release has come from genetic and physiological study in which the Drosophila CSP null mutant fails to elicit synaptic potential upon high frequency stimulation. CSP null mutants have a lethal phenotype and for the small percentage of mutant flies that survive, they become paralyzed and die at elevated temperature.
• Antibody come from
  Influenza B (whole virus) virions.
• Other description
  Supplied as a liquid in PBS, 1% BSA, 0.002% Thirmerosal. Labeled with Horseradish Peroxidase. Ammonium Sulfate Precipitation
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Cysteine string protein (CSP) Alpha antibody DNAJC5 alpha Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human, Rat, Mouse
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot, ELISA
• Antibody s suited for
  ELISA: 1:1000 Western Blot: 1:200 Immunohistochemistry: 1:200_x000B_Optimal concentration should be evaluated by serial dilutions._x000B_May be stored at 4¡C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20¡C.
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  The Rabbit anti Cysteine string protein (CSP) Alpha antibody DNAJC5 alpha is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Cys or cysteines ChEMBL54943
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  Cysteine   string   protein   CSP   Alpha   DNAJC5   alpha  
• Gene symbol
  DNAJC5G, DNAJC5B, DNAJC5, GZMH, GZMB
• Short name
  Rabbit anti Cysteine string protein (CSP) Alpha antibody DNAJC5 alpha
• Technique
  Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Cysteine string protein (CSP) a (antibody to-) DnaJ (Hsp40) homolog, subfamily C, member 5 a
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  DnaJ (Hsp40) homolog, subfamily C, member 5, DNAJC5 and IDBG-87436 and ENSG00000101152 and 80331, ATP-dependent protein binding, Plasma membranes, Dnajc5 and IDBG-214134 and ENSMUSG00000000826 and 13002, DNAJC5 and IDBG-640468 and ENSBTAG00000015796 and 282216

Gene info

• Identity
  HGNC:24844
• Gene
  DNAJC5G
• Long gene name
  DnaJ heat shock protein family (Hsp40) member C5 gamma
• Synonyms gene name
  • DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
• Synonyms
  • FLJ40417
  • CSP-gamma
• GenBank acession
  • AF368277
• Locus
  2p23.3
• Discovery year
  2004-03-16
• Entrez gene record
  285126
• RefSeq identity
  • NM_173650
• Classification
  • DNAJ (HSP40) heat shock proteins
• VEGA ID
  OTTHUMG00000097079

Gene info

• Identity
  HGNC:24138
• Gene
  DNAJC5B
• Long gene name
  DnaJ heat shock protein family (Hsp40) member C5 beta
• Synonyms gene name
  • DnaJ (Hsp40) homolog, subfamily C, member 5 beta
• Synonyms
  • MGC26226
  • CSP-beta
• GenBank acession
  • AF368276
• Locus
  8q13.1
• Discovery year
  2004-03-16
• Entrez gene record
  85479
• Pubmed identfication
  • 29182667
• RefSeq identity
  • NM_033105
• Classification
  • DNAJ (HSP40) heat shock proteins
• VEGA ID
  OTTHUMG00000164470

Gene info

• Identity
  HGNC:16235
• Gene
  DNAJC5
• Long gene name
  DnaJ heat shock protein family (Hsp40) member C5
• Synonyms gene
  • CLN4
• Synonyms gene name
  • ceroid-lipofuscinosis, neuronal 4 (Kufs disease)
  • DnaJ (Hsp40) homolog, subfamily C, member 5
• Synonyms
  • FLJ00118
  • FLJ13070
  • DNAJC5A
• Locus
  20q13.33
• Discovery year
  2001-07-17
• Entrez gene record
  80331
• RefSeq identity
  • NM_025219
• Classification
  • DNAJ (HSP40) heat shock proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000033007
• Locus Specific Databases
  • Neuronal Ceroid Lipofuscinoses; NCL Mutations
  • LRG_831

Gene info

• Identity
  HGNC:4710
• Gene
  GZMH
• Long gene name
  granzyme H
• Synonyms gene
  • CTSGL2
• Synonyms gene name
  • granzyme H (cathepsin G-like 2, protein h-CCPX)
• Synonyms
  • CGL-2
  • CCP-X
  • CTLA1
  • CSP-C
• Synonyms name
  • cathepsin G-like 2, protein h-CCPX
• GenBank acession
  • M72150
• Locus
  14q12
• Discovery year
  1990-04-09
• Entrez gene record
  2999
• Pubmed identfication
  • 2049336
• RefSeq identity
  • NM_033423
• Classification
  • Granule associated serine proteases of immune defence
• VEGA ID
  OTTHUMG00000140185

Gene info

• Identity
  HGNC:4709
• Gene
  GZMB
• Long gene name
  granzyme B
• Synonyms gene
  • CTLA1
  • CSPB
• Synonyms gene name
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
• Synonyms
  • CCPI
  • CGL-1
  • CSP-B
  • CGL1
  • CTSGL1
  • HLP
  • SECT
• Synonyms name
  • fragmentin 2
  • cytotoxic serine protease B
  • cathepsin G-like 1
  • T-cell serine protease 1-3E
  • granzyme 2
  • cytotoxic T-lymphocyte-associated serine esterase 1
• GenBank acession
  • BC030195
• Locus
  14q12
• Discovery year
  1989-05-12
• Entrez gene record
  3002
• Pubmed identfication
  • 2323780
• RefSeq identity
  • NM_004131
• Classification
  • Granule associated serine proteases of immune defence
• VEGA ID
  OTTHUMG00000029369

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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