Anti-NEUROD2 Antibody

• Catalog number
  A1648-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  NEUROD2
• Target Alternative Name
  BHLHA1; NDRF; Neurogenic differentiation factor 2; NeuroD2; Class A basic helix-loop-helix protein 1; bHLHa1; NeuroD-related factor; NDRF
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NEUROD2
• Accession
  Q15784
• Gene Id
  4761
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB, IHC, IP
• Positive Control
  WB: Jurkat; mouse brain; rat brain whole cell lysates, IHC: human brain tissue
• Application And Usages
  WB; 1:500 – 1:1000, IHC; 1:100 – 1:200, IP; 1:10 – 1:100
• Description
  Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NEUROD2  
• Gene symbol
  NEUROD2
• Short name
  Anti-NEUROD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toNEUROD2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7763
• Gene
  NEUROD2
• Long gene name
  neuronal differentiation 2
• Synonyms gene name
  • neurogenic differentiation 2
• Synonyms
  • NDRF
  • bHLHa1
• GenBank acession
  • U58681
• Locus
  17q12
• Discovery year
  1997-04-10
• Entrez gene record
  4761
• Pubmed identfication
  • 9119405
• RefSeq identity
  • NM_006160
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000133211

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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