TRAILR4 (Tumor Necrosis Factor Receptor Superfamily Member 10D, Decoy Receptor 2, DcR2, TNF-related Apoptosis-inducing Ligand Receptor 4, TRAIL Receptor 4, TRAIL-R4, TRAIL Receptor With a Truncated Death Domain, CD264, TNFRSF10D, DCR2, TRAILR4, TRUNDD, UN Antibody

• Catalog number
  GEN632240
• Price
  Please ask
• Size
  100 Tests

• Also known as
  TRAILR4
• Other names
  tumor necrosis factor receptor superfamily member 10D; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10D; TRAIL receptor 4; decoy receptor 2; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4
• Gene name synonims
  TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4
• Other gene names
  TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  11C53
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human TRAIL R4.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by immunoaffinity chromatography.
• Form Appearance
  Supplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
• Concentration
  N/A
• Storage and shipping
  May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
• French translation
  anticorps

• Gene target
  TRAILR4   Tumor   Necrosis   Factor   Receptor   Superfamily   Member   10D   Decoy   Receptor   DcR2   TNF-related   Ligand   Receptor   TRAIL   Receptor   TRAIL-R4   TRAIL   Receptor   With   Truncated   Death   Domain   CD264   TNFRSF10D   DCR2   TRAILR4   TRUNDD  
• Gene symbol
  TNFRSF10D, TNFSF10, TNF, TNFRSF1A, TNFRSF10B, TNFRSF1B, LTBR, CCR6
• Short name
  TRAILR4 (Tumor Necrosis Factor Receptor Superfamily Member 10D, Decoy Receptor 2, DcR2, TNF- Apoptosis- Ligand Receptor 4, TRAIL Receptor 4, TRAIL-R4, TRAIL Receptor With a Truncated Death Domain, CD264, TNFRSF10D, DCR2, TRAILR4, TRUNDD, UN Antibody
• Technique
  apoptosis, Antibody, antibodies against human proteins, antibodies for, apoptosis pathway
• Alternative name
  Anti-TRAILR4 (Tumor Necrosis Factor Receptor Superfamily Member 10D, Decoy Receptor 2, DcR2, TNF-related Apoptosis-inducing Ligand Receptor 4, TRAIL Receptor 4, TRAIL-R4, TRAIL Receptor With a Truncated Death Domain, CD264, TNFRSF10D, DCR2, TRAILR4, TRUNDD, UN
• Alternative technique
  celldeath, antibodies
• Alternative to gene target
  tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain, CD264 and DCR2 and TRAIL-R4 and TRAILR4 and TRUNDD, TNFRSF10D and IDBG-11632 and ENSG00000173530 and 8793, TRAIL binding, Plasma membranes
• Tissue
  tumor

Gene info

• Identity
  HGNC:11907
• Gene
  TNFRSF10D
• Long gene name
  TNF receptor superfamily member 10d
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
• Synonyms
  • DcR2
  • TRUNDD
  • TRAILR4
  • CD264
• GenBank acession
  • AF029761
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8793
• Pubmed identfication
  • 9382840
  • 9537512
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097845

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

Gene info

• Identity
  HGNC:1607
• Gene
  CCR6
• Long gene name
  C-C motif chemokine receptor 6
• Synonyms gene
  • STRL22
• Synonyms gene name
  • chemokine (C-C motif) receptor 6
• Synonyms
  • CKR-L3
  • GPR-CY4
  • CMKBR6
  • GPR29
  • DRY-6
  • DCR2
  • BN-1
  • CD196
• GenBank acession
  • U68030
• Locus
  6q27
• Discovery year
  1997-04-21
• Entrez gene record
  1235
• Pubmed identfication
  • 8886020
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000016015

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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