anti-CENPO Antibody

• Catalog number
  5433
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  CENPO Antibody: Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.
• Gene names
  CENPO Antibody: CENP-O, MCM21R, ICEN-36, ICEN36, Centromere protein O, Interphase centromere complex protein 36, CENP-O
• Antibodie s label
  unlabelled serum
• Purity
  CENPO Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  CENPO antibody was made against a 16 amino acid synthetic peptide from near the center of human CENPO.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  CENPO antibody can be used for detection of CENPO by Western blot at 1 - 2 ug/mL.
• Suspention pH azide
  CENPO Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CENPO antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  13236565
• Ncbi nr
  NP_077298
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  79172
• GENE symbol
  CENPO
• Antigene name
  centromere protein O
• Source
  Homo sapiens
• Protein nr
  Q9BU64
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CENPO  
• Gene symbol
  CENPO
• Short name
  anti-CENPO Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCENPO (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28152
• Gene
  CENPO
• Long gene name
  centromere protein O
• Synonyms
  • MGC11266
  • CENP-O
• GenBank acession
  • AK027859
• Locus
  2p23.3
• Discovery year
  2006-06-15
• Entrez gene record
  79172
• Pubmed identfication
  • 16622420
  • 16622419
• RefSeq identity
  • NM_024322
• Classification
  • Constitutive centromere associated network
• VEGA ID
  OTTHUMG00000125525

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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