UNC2170

  • Catalog number
    2889-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    3-Bromo-N-(3-(tert-butylamino)propyl)benzamide
  • Description
    UNC-2170 is a micromolar ligand for the Methyl-lysine Binding Protein, 53BP1. UNC-2170 displays 17-fold selectivity for 53BP1 as compared to other methyl-lysine (Kme) binding proteins tested.  It functions as a 53BP1 antagonist in cellular lysates and shows cellular activity by suppressing class switch recombination, a process which requires a functional 53BP1 tudor domain.
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₄H₂₁BrN₂O
  • Molecular Weight
    313.23
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A ligand for the Methyl-lysine Binding Protein, 53BP1.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • SMILES
    BrC1=CC(C(NCCCNC(C)(C)C)=O)=CC=C1
  • InChi
    InChI=1S/C14H21BrN2O/c1-14(2,3)17-9-5-8-16-13(18)11-6-4-7-12(15)10-11/h4,6-7,10,17H,5,8-9H2,1-3H3,(H,16,18)
  • InChi Key
    XUFUVCIZFNREBI-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    UNC2170  
  • Short name
    UNC2170
  • Alternative name
    UNC2170
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