UNC2170
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Catalog number2889-5
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PricePlease ask
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Size5 mg
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Alternative_name3-Bromo-N-(3-(tert-butylamino)propyl)benzamide
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DescriptionUNC-2170 is a micromolar ligand for the Methyl-lysine Binding Protein, 53BP1. UNC-2170 displays 17-fold selectivity for 53BP1 as compared to other methyl-lysine (Kme) binding proteins tested. It functions as a 53BP1 antagonist in cellular lysates and shows cellular activity by suppressing class switch recombination, a process which requires a functional 53BP1 tudor domain.
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₄H₂₁BrN₂O
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Molecular Weight313.23
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA ligand for the Methyl-lysine Binding Protein, 53BP1.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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SMILESBrC1=CC(C(NCCCNC(C)(C)C)=O)=CC=C1
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InChiInChI=1S/C14H21BrN2O/c1-14(2,3)17-9-5-8-16-13(18)11-6-4-7-12(15)10-11/h4,6-7,10,17H,5,8-9H2,1-3H3,(H,16,18)
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InChi KeyXUFUVCIZFNREBI-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameUNC2170
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Alternative nameUNC2170
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