Cryptotanshinone

  • Catalog number
    2429-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    1,2,6,7,8,9-Hexahydro-1,6,6-trimeth​yl[1,2-b]furan-10,11-dione
  • Description
    Cryptotanshinone is a natural product isolated from the roots of Salvia miltiorrhiza Bunge that displays a variety of biological activities. Displays antitumor activity by inhibition of STAT3 (IC₅₀ = 4.6 µM). Also displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also inhibits acetylcholinesterase (AChE) (IC₅₀ = 4.09 μM) and reduction in Aβ peptide generation.
  • CAS Number
    35825-57-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₉H₂₀O₃
  • Molecular Weight
    296.36
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~ 5 mg/ml)
  • Handling
    Protect from light and air
  • Tag Line
    A STAT3 inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD07636810
  • PubChem CID
    160254
  • SMILES
    CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
  • InChi
    InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
  • InChi Key
    GVKKJJOMQCNPGB-JTQLQIEISA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Cryptotanshinone
  • Alternative name
    Cryptotanshinone
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