Cytokeratin, Acidic (Type I or LMW) Antibody
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Catalog numberGEN438053
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PricePlease ask
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Size100ug
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Also known asCytokeratin
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Other nameskeratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 10; keratin, type I cytoskeletal 10; CK-10; keratin-10; cytokeratin 10; keratin 10; Cytokeratin-10; CK-10; Keratin-10; K10
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameKRT10
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Gene name synonimsKRT14; KRT15; KRT6; KRT19
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Other gene namesKRT10; KRT10; BIE; EHK; K10; KPP; BCIE; CK10; KPP; CK-10; K10
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneAE-1
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens), Monkey, Cow, Dog, Rabbit (Oryctolagus cuniculus), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken, Turtle.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityThis MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceN/A
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ConcentrationN/A
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Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology (IH)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolACP1
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Short nameCytokeratin, Acidic ( I LMW) Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-Cytokeratin, Acidic (Type I or LMW)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameacid phosphatase 1
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Synonyms gene name
- acid phosphatase 1, soluble
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Acid phosphatases
- Class II Cys-based phosphatases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data