Interleukin 1 beta, Recombinant, Human

Quantity:

Products_type

Recombinant Protein
Products_short_name

[Interleukin 1 beta]
Other_names

[interleukin-1 beta; Interleukin-1 beta; interleukin-1 beta; IL-1 beta; interleukin 1 beta; lymphocyte proliferation-potentiating factor; Lymphocyte proliferation-potentiating factor]
Other_gene_names

[IL1B; IL1B; IL1-BETA]
Purity

Highly Purified95% by SDS-PAGE.
Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 50% glycerol
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Interleukin beta
Gene symbol

IL12RB1, IL1B, CASP1
Short name

Interleukin 1 beta, Recombinant,
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

Human, Recombinant, E Coli
Species

Human, Humans
Alternative name

Interleukin 1 b, Rec., H. sapiens
Alternative technique

rec

Quantity:

Identity

HGNC:5971
Gene

IL12RB1
Long gene name

interleukin 12 receptor subunit beta 1
Synonyms gene
- IL12RB
Synonyms gene name
- interleukin 12 receptor, beta 1
Synonyms
- CD212
GenBank acession
- U03187
Locus

19p13.11
Discovery year

1995-09-14
Entrez gene record

3594
Pubmed identfication
- 9284929
Classification
- Fibronectin type III domain containing
- CD molecules
- Interleukin receptors
VEGA ID

OTTHUMG00000183417
Locus Specific Databases
- IL12RB1base: Mutation registry for Interleukin-12 receptor ß1 deficiency
- LRG_72

Identity

HGNC:1499
Gene

CASP1
Long gene name

caspase 1
Synonyms gene
- IL1BC
Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
Synonyms
- ICE
Synonyms name
- caspase-1
- interleukin 1, beta, convertase
GenBank acession
- U13697
Locus

11q22.3
Discovery year

1992-05-07
Entrez gene record

834
Pubmed identfication
- 1373520
- 9250871
RefSeq identity
- NM_033292
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000048072

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data