SL0101
-
Catalog numberB1895-5
-
PricePlease ask
-
Size5 mg
-
-
Alternative_name3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydro-2-(4-hydroxyphenyl)-4H-1benzopyran-4-one
-
DescriptionSL0101 is a potent and selective inhibitor of ribosomal S6 kinase (RSK) (IC₅₀ = 89 nM for RSK2). Does not have any effect on upstream kinases such as MEK, Raf and PKC. Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.
-
CAS Number77307-50-7
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₂₅H₂₄O₁₂
-
Molecular Weight516.46
-
Cell PermeableYes
-
Purity≥98% by HPLC
-
SolubilitiesDMSO
-
HandlingProtect from air and light
-
Tag LineA potent and selective inhibitor of ribosomal S6 kinase (RSK)
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
PubChem CID10459196
-
SMILESCC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)OC(=O)C)OC(=O)C
-
InChiInChI=1S/C25H24O12/c1-10-21(34-11(2)26)24(35-12(3)27)20(32)25(33-10)37-23-19(31)18-16(30)8-15(29)9-17(18)36-22(23)13-4-6-14(28)7-5-13/h4-10,20-21,24-25,28-30,32H,1-3H3/t10-,20+,21-,24-,25-/m0/s1
-
InChi KeySXOZSDJHGMAEGZ-IGKKHSBFSA-N
-
Gene target
-
Short nameSL0101
-
Alternative nameSL0101
-