SL0101

  • Catalog number
    B1895-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydro-2-(4-hydroxyphenyl)-4H-1benzopyran-4-one
  • Description
    SL0101 is a potent and selective inhibitor of ribosomal S6 kinase (RSK) (IC₅₀ = 89 nM for RSK2). Does not have any effect on upstream kinases such as MEK, Raf and PKC.  Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.
  • CAS Number
    77307-50-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₂₄O₁₂
  • Molecular Weight
    516.46
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective inhibitor of ribosomal S6 kinase (RSK)
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    10459196
  • SMILES
    CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)OC(=O)C)OC(=O)C
  • InChi
    InChI=1S/C25H24O12/c1-10-21(34-11(2)26)24(35-12(3)27)20(32)25(33-10)37-23-19(31)18-16(30)8-15(29)9-17(18)36-22(23)13-4-6-14(28)7-5-13/h4-10,20-21,24-25,28-30,32H,1-3H3/t10-,20+,21-,24-,25-/m0/s1
  • InChi Key
    SXOZSDJHGMAEGZ-IGKKHSBFSA-N
  • Gene target
    SL0101  
  • Short name
    SL0101
  • Alternative name
    SL0101
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