CD98 monoclonal antibody
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Catalog number1P-268-T100
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PricePlease ask
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Size100 assays
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Long nameMouse Monoclonal Antibody against Human CD98, Clone: MEM-108
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AntigenCD98
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Species reactivityHuman (Homo sapiens)
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Negative species reactivityat the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
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ClonalityMonoclonal Antibody (Mab)
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CloneMEM-108
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ApplicationsFC, IP, IHC(P)
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ImmunogenRAJI human Burkitt's lymphoma cell line
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Format conjugationPE
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SpecificityThe antibody MEM-108 reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets._x000D_ HLDA VI; WS Code BP 409 _x000D_ HLDA VI; WS Code NL N-L017 _x000D_
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Research areaCD and Related Antigens (Human)
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Storage bufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
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Shipping and storageMouse Monoclonal Antibody against Human CD98, Clone: MEM-108 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
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BackgroundCD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
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Purity> 95% (by SDS-PAGE)
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Purification methodPurified by affinity chromatography
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References*Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
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PropertiesIf you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translationanticorps
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Gene target
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Gene symbolSLC7A5, SLC3A2
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Short nameAnti-CD98 Mab
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TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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HostMouse (Mus musculus)
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IsotypeIgG1
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Alternative nameMouse Monoclonal to CD98
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namesolute carrier family 7 member 5
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Synonyms gene name
- solute carrier family 7 (amino acid transporter light chain, L system), member 5
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
- CD molecules
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 3 member 2
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Synonyms gene
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Synonyms gene name
- solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
- solute carrier family 3 (amino acid transporter heavy chain), member 2
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data