Lonidamine

• Catalog number
  B1058-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  1-[(2,4-Dichlorophenyl)methyl]-1H-i​ndazole-3-carboxylic acid
• Description
  Lonidamine is a derivative of indazole-3-carboxylic acid that inhibits glycolysis by the inactivation of hexokinase, an enzyme that catalyzes glucose as the first step in glycolysis. Also blocks CFTR Cl- channels in vitro. Acts as an anticancer and antispermatogenic agent in vitro and in vivo.
• CAS Number
  50264-69-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₁₀Cl₂N₂O₂
• Molecular Weight
  321.16
• Cell Permeable
  Yes
• Purity
  ≥95%
• Solubilities
  DMSO (>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A hexokinase and glycolysis inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00866285
• PubChem CID
  39562
• PubChem CID Link
• SMILES
  C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O
• InChi
  InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
• InChi Key
  WDRYRZXSPDWGEB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Lonidamine  
• Short name
  Lonidamine
• Alternative name
  Lonidamine

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