CDKN2C Antibody

• Catalog number
  F41067-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CDKN2C
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the CDKN2C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CDKN2C antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P42773
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
• Immunogen
  A portion of amino acids 113-139 from the human protein was used as the immunogen for this CDKN2C antibody.
• Storage
  Aliquot the CDKN2C antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDKN2C  
• Gene symbol
  CDKN2C
• Short name
  Anti-CDKN2C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CDKN2C
• Alternative technique
  antibodies
• Alternative to gene target
  cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), INK4C and p18 and p18-INK4C, CDKN2C and IDBG-98423 and ENSG00000123080 and 1031, protein kinase binding, nuclei, Cdkn2c and IDBG-174648 and ENSMUSG00000028551 and 12580, CDKN2C and IDBG-639655 and ENSBTAG00000011059 and 505691

Gene info

• Identity
  HGNC:1789
• Gene
  CDKN2C
• Long gene name
  cyclin dependent kinase inhibitor 2C
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
• Synonyms
  • INK4C
  • p18
• GenBank acession
  • BC000598
• Locus
  1p32.3
• Discovery year
  1995-07-06
• Entrez gene record
  1031
• Pubmed identfication
  • 8001816
  • 9636670
• RefSeq identity
  • NM_001262
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000008046

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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