Avasimibe

• Catalog number
  9506-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  [2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulfamate; CI-1011; PD 148515
• Description
  Avasimibe is an orally bioavailable inhibitor of the acyl coenzyme A: cholesterol acyltransferase (ACAT) (IC₅₀ = 60 nM). Avasimibe also inhibits major drug metabolizing enzymes such as CYP2C9 (IC₅₀ = 2.9 µM ), CYP1A2 (IC₅₀ = 13.9 µM), and CYP2C19 (IC₅₀ = 26.5 µM).
• CAS Number
  166518-60-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₉H₄₃NO₄S
• Molecular Weight
  501.72
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>35 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00934956
• PubChem CID
  166558
• PubChem CID Link
• SMILES
  CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C
• InChi
  InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)
• InChi Key
  PTQXTEKSNBVPQJ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Avasimibe  
• Short name
  Avasimibe
• Alternative name
  Avasimibe

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