Notch 1 Antibody
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Catalog number3881-100
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PricePlease ask
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Size100 µg
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Antibody TargetNotch 1
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Target Alternative NameNotch-1, Notch 1, NOTCH1, TAN1, hN1
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide corresponding to residues surrounding amino acid 1760 of mouse Notch1
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AccessionNP_032740
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Gene Id18128
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
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DescriptionNotch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2, Notch 3 and Notch 4. The membrane ligand for Notch includes Jagged 1, Jagged 2 and Delta. Notch 1 is a 270 kDa transmembrane receptor that can be activated by Delta (Dl) ligand. Activation of Notch 1 will result in the proteolytic cleavage of Notch 1 into a 120 kDa length protein.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNOTCH1, NOTCH2P1, SBNO1
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Short nameNotch 1 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameNotch 1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namenotch receptor 1
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Synonyms gene
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Synonyms gene name
- Notch (Drosophila) homolog 1 (translocation-associated)
- Notch homolog 1, translocation-associated (Drosophila)
- notch 1
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GenBank acession
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Locus
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Discovery year1992-02-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Notch receptors
- MicroRNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenotch 2 pseudogene 1
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Locus
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Discovery year2012-07-25
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namestrawberry notch homolog 1
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Synonyms gene name
- sno, strawberry notch homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-08-11
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
