anti- EIF4G1 antibody

• Catalog number
  FNab02724
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
• Immunogen
  eukaryotic translation initiation factor 4 gamma, 1
• Synonyms
  EIF4F, EIF4G, EIF4GI
• Calculated MW
  200 kDa
• Uniprot ID
  Q04637
• Specificity
  Human
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human breast cancer using FNab02724(EIF4G1 antibody) at dilution of 1:100
• Image4
  HeLa cells were subjected to SDS PAGE followed by western blot with FNab02724(EIF4G1 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EIF4G1  
• Gene symbol
  EIF4G1
• Short name
  anti- EIF4G1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- EIF4G1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3296
• Gene
  EIF4G1
• Long gene name
  eukaryotic translation initiation factor 4 gamma 1
• Synonyms gene
  • EIF4G
  • EIF4F
• Synonyms gene name
  • eukaryotic translation initiation factor 4 gamma, 1
• Synonyms
  • p220
  • PARK18
• GenBank acession
  • D12686
• Locus
  3q27.1
• Discovery year
  1993-06-17
• Entrez gene record
  1981
• Pubmed identfication
  • 1429670
  • 9372926
  • 21907011
• RefSeq identity
  • NM_182917
• Classification
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000156784

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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