GTF2H4 (General Transcription Factor IIH Subunit 4, Basic Transcription Factor 2 52 kDa Subunit, BTF2 p52, General Transcription Factor IIH Polypeptide 4, TFIIH Basal Transcription Factor Complex p52 Subunit)

  • Catalog number
    MBS643434
  • Price
    Please ask
  • Size
    5x0.05 mg
  • Products_type
    Antibody
  • Products_short_name
    [GTF2H4]
  • Products_name_syn
    [Anti -GTF2H4 (General Transcription Factor IIH Subunit 4, Basic Transcription Factor 2 52 kDa Subunit, BTF2 p52, General Transcription Factor IIH Polypeptide 4, TFIIH Basal Transcription Factor Complex p52 Subunit)]
  • Other_names
    [general transcription factor IIH subunit 4; General transcription factor IIH subunit 4; general transcription factor IIH subunit 4; BTF2 p52; basic transcription factor 2 52 kDa subunit; general transcription factor IIH polypeptide 4; TFIIH basal transcription factor complex p52 subunit; general transcription factor IIH, polypeptide 4, 52kDa; Basic transcription factor 2 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4; TFIIH basal transcription factor complex p52 subunit]
  • Other_gene_names
    [GTF2H4; GTF2H4; P52; TFB2; TFIIH; BTF2 p52]
  • Clonality
    Polyclonal
  • Reactivity
    Human
  • Specificity
    Recognizes human GTF2H4.
  • Purity
    Affinity Purified Purified by Protein A affinity chromatography.
  • Form
    Supplied as a liquid in PBS, pH 7.2.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    Western Blot (WB), Immunofluorescence (IF)
  • Description
    Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The kilo Daltons subunit weight of GTF2H4 (General Transcription Factor IIH Subunit 4, Transcription Factor 2 52 Subunit, BTF2 p52, General Transcription Factor IIH Polypeptide 4, TFIIH Basal Transcription Factor Complex p52 Subunit) compared to your protein ladder can be shifted a little due to electrophoresis effects. 1 kDa = 1000 g/mol protein, The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene target
    GTF2H4   General   Transcription   Factor   IIH   Subunit   Transcription   Factor   Subunit   BTF2   p52   General   Transcription   Factor   IIH   Polypeptide   TFIIH   Basal   Transcription   Factor   Complex   p52   Subunit  
  • Gene symbol
    GTF2H4, GTF2H1, GTF2H3, GTF2H2, BTN2A2, ERCC3, GTF2H5
  • Short name
    GTF2H4 (General Transcription Factor IIH Subunit 4, Transcription Factor 2 52 Subunit, BTF2 p52, General Transcription Factor IIH Polypeptide 4, TFIIH Basal Transcription Factor Complex p52 Subunit)
  • Host
    Mouse
  • Isotype
    IgG
  • Alternative name
    GTF2H4 (General Transcription Factor IIH functionnal sequence 4, Basic Transcription Factor 2 52 kiloDalton functionnal sequence, BTF2 p52, General Transcription Factor IIH multipeptide 4, TFIIH Basal Transcription Factor aggregate p52 functionnal sequence)
Gene info
  • Identity
    HGNC:4658
  • Gene
    GTF2H4
  • Long gene name
    general transcription factor IIH subunit 4
  • Synonyms gene name
    • general transcription factor IIH, polypeptide 4 (52kD subunit)
    • general transcription factor IIH, polypeptide 4, 52kDa
  • Synonyms
  • GenBank acession
  • Locus
    6p21.33
  • Discovery year
    1998-08-19
  • Entrez gene record
    2968
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nucleotide excision repair
    • General transcription factor IIH complex subunits
  • VEGA ID
    OTTHUMG00000031043
Gene info
  • Identity
    HGNC:4655
  • Gene
    GTF2H1
  • Long gene name
    general transcription factor IIH subunit 1
  • Synonyms gene name
    • general transcription factor IIH, polypeptide 1 (62kD subunit)
    • general transcription factor IIH, polypeptide 1, 62kDa
  • Synonyms
  • Locus
    11p15.1
  • Discovery year
    1993-08-16
  • Entrez gene record
    2965
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • General transcription factor IIH complex subunits
    • Nucleotide excision repair
  • VEGA ID
    OTTHUMG00000167690
Gene info
  • Identity
    HGNC:4657
  • Gene
    GTF2H3
  • Long gene name
    general transcription factor IIH subunit 3
  • Synonyms gene name
    • general transcription factor IIH, polypeptide 3 (34kD subunit)
    • general transcription factor IIH, polypeptide 3, 34kDa
  • Synonyms
  • GenBank acession
  • Locus
    12q24.31
  • Discovery year
    1994-11-01
  • Entrez gene record
    2967
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • General transcription factor IIH complex subunits
    • Nucleotide excision repair
  • VEGA ID
    OTTHUMG00000168697
Gene info
  • Identity
    HGNC:4656
  • Gene
    GTF2H2
  • Long gene name
    general transcription factor IIH subunit 2
  • Synonyms gene name
    • general transcription factor IIH, polypeptide 2 (44kD subunit)
    • general transcription factor IIH, polypeptide 2, 44kDa
  • Synonyms
  • GenBank acession
  • Locus
    5q13.2
  • Discovery year
    1994-11-01
  • Entrez gene record
    2966
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nucleotide excision repair
    • General transcription factor IIH complex subunits
  • VEGA ID
    OTTHUMG00000164542
Gene info
Gene info
  • Identity
    HGNC:3435
  • Gene
    ERCC3
  • Long gene name
    ERCC excision repair 3, TFIIH core complex helicase subunit
  • Synonyms gene name
    • excision repair cross-complementing rodent repair deficiency, complementation group 3
    • excision repair cross-complementation group 3
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
    2q14.3
  • Discovery year
    2001-06-22
  • Entrez gene record
    2071
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • DNA helicases
    • General transcription factor IIH complex subunits
    • Xeroderma pigmentosum complementation groups
    • ERCC excision repair associated
  • VEGA ID
    OTTHUMG00000131530
  • Locus Specific Databases
Gene info
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GTF2H4 General Transcription Factor IIH Subunit 4 Transcript
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