Human CellExp™ Netrin-1, human recombinant

  • Catalog number
    7575-10
  • Price
    Please ask
  • Size
    10 ug
  • Synonyms
    NTN1
  • Alternative_names
    NTN1
  • Description
    Involved in tumorigenesis by regulating apoptosis.
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    ≥95%
  • Assay
    SDS-PAGE
  • Activity Specifications test method
    Induces axon outgrowth.
  • Biological activity
    Induces axon outgrowth.
  • Results
    Induces axon outgrowth.
  • Molecular Weight
    ~80.0 kDa. Human netrin-1 (aa 25-604) is fused at the C-terminus to a FLAG®-tag.
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    6 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized in PBS with trehalose and Brij 35.
  • Reconstitution Instructions
    Reconstitute with 100 ul sterile distilled water.
  • Background Information
    Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    CellExp™ Netrin-1, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ Netrin-1, H. sapiens Rec.
  • Alternative technique
    rec
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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