BMS-303141

  • Catalog number
    2821-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide
  • Description
    BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL) (IC₅₀ = 0.13 µM for human recombinant ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC₅₀ of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model
  • CAS Number
    943962-47-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₉H₁₅Cl₂NO₄S
  • Molecular Weight
    424.3
  • Cell Permeable
    yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~10 mg/ml) or EtOH (~ 20 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent inhibitor of ATP citrate lyase (ACL)
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    16747776
  • SMILES
    COC1=C(C=C(C=C1)C2=CC=CC=C2)NS(=O)(=O)C3=CC(=CC(=C3O)Cl)Cl
  • InChi
    InChI=1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3
  • InChi Key
    SIIPNDKXZOTLEA-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    BMS-303141
  • Alternative name
    BMS-303141
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