BMS-303141
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Catalog number2821-50
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PricePlease ask
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Size50 mg
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Alternative_name3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide
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DescriptionBMS-303141 is a potent inhibitor of ATP citrate lyase (ACL) (IC₅₀ = 0.13 µM for human recombinant ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC₅₀ of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model
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CAS Number943962-47-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₉H₁₅Cl₂NO₄S
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Molecular Weight424.3
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Cell Permeableyes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~10 mg/ml) or EtOH (~ 20 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent inhibitor of ATP citrate lyase (ACL)
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID16747776
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SMILESCOC1=C(C=C(C=C1)C2=CC=CC=C2)NS(=O)(=O)C3=CC(=CC(=C3O)Cl)Cl
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InChiInChI=1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3
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InChi KeySIIPNDKXZOTLEA-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBMS-303141
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Alternative nameBMS-303141
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