DiscoveryPak™ Hedgehog (Hh) Signaling Pathway Inhibitors Set

  • Catalog number
    K868-6
  • Price
    Please ask
  • Size
    Inhibitors
  • Alternative_name
    Hedgehog (Hh) Signaling Pathway Inhibitors Set
  • Description
    A convenient set consisting of five Hedgehog (Hh) signaling pathway inhibitors and a negative control. The five inhibitors are: 50 µg of Cyclopamine-KAAD (Cat. No. 1910-50), 5 mg of GANT58 (Cat. No. 1812-5), 5 mg of GDC-0449 (Cat. No. 1890-5), 1 mg of Hh Signaling Pathway Antagonist (Cat. No. 1726-1), 1 mg of JK 184 (Cat. No. 1726-1). Also provided is 25 mg of Tomatidine hydrochloride (Cat. No. 1893-25) which can act as a negative control.
  • CAS Number
    See under the individual product
  • Structure Available
    See under the individual product
  • Salt Form
    No
  • Molecular Formula
    See under the individual product
  • Molecular Weight
    See under the individual product
  • Cell Permeable
    Yes
  • Purity
    See under the individual product
  • Solubilities
    See under the individual product
  • Handling
    Protect from air and light
  • Tag Line
    A Hedgehog (Hh) signaling pathway inhibitors set
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • SMILES
    N/A
  • InChi
    N/A
  • InChi Key
    N/A
  • MSDS Available
    Yes
  • Additional description
    Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
MeSH Data
  • Name
  • Concept
    Scope note: A membrane or barrier with micrometer sized pores used for separation purification processes.
  • Tree numbers
    • E05.196.454.403
    • E07.560
  • Qualifiers
    parasitology, microbiology, ethics, virology, trends, veterinary, history, classification, economics, standards, supply & distribution, adverse effects, statistics & numerical data
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