AZD-3463
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Catalog number2371-25
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PricePlease ask
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Size25 mg
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Alternative_name2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl
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DescriptionAZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).
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CAS Number1356962-20-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₄H₂₅ClN₆O
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Molecular Weight448.95
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~20 mg/ml)
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HandlingProtect from light and moisture
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Tag LineA potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID56599293
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SMILESCOC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
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InChiInChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)
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InChi KeyGCYIGMXOIWJGBU-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameAZD-3463
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Alternative nameAZD-3463
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