AZD-3463

  • Catalog number
    2371-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl
  • Description
    AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).
  • CAS Number
    1356962-20-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₅ClN₆O
  • Molecular Weight
    448.95
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~20 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    A potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    56599293
  • SMILES
    COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
  • InChi
    InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)
  • InChi Key
    GCYIGMXOIWJGBU-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    AZD-3463
  • Alternative name
    AZD-3463
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