KCNQ2 Antibody, ALEXA FLUOR 350

• Catalog number
  bs-11728R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  KCNQ2 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-KCNQ2 PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  KCNQ2
• Specificity
  This is a highly specific antibody against KCNQ2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNQ2
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Epilepsy affects about 0.5% of the world’s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  BFNC; BFNS1; EBN 1; EBN; EBN1; EIEE7; ENB 1; ENB1; HNSPC; KCNA 11; KCNA11; KCNQ 2; Kcnq2; KCNQ2_HUMAN; KQT like 2; KQT-like 2; KV7.2; KVEBN 1; KVEBN1; KvLQT 2; KvLQT2; Neuroblastoma specic potassium channel alpha subunit KvLQT2; Neuroblastoma specic potassium channel protein; Neuroblastoma specic potassium channel subunit alpha; Neuroblastoma specic potassium channel subunit alpha KvLQT2; Neuroblastoma-specic potassium channel subunit alpha KvLQT2; Potassium voltage gated channel KQT like protein 2; Potassium voltage gated channel KQT like subfamily member 2; Potassium voltage gated channel subfamily KQT member 2; Potassium voltage-gated channel subfamily KQT member 2; Voltage gated potassium channel subunit Kv7.2; Voltage-gated potassium channel subunit Kv7.2.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  KCNQ2  
• Gene symbol
  KCNQ2-AS1, KCNQ2
• Short name
  Anti-KCNQ2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  KCNQ2 Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40321
• Gene
  KCNQ2-AS1
• Long gene name
  KCNQ2 antisense RNA 1
• Locus
  20q13.33
• Discovery year
  2019-08-15
• Entrez gene record
  105372720
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6296
• Gene
  KCNQ2
• Long gene name
  potassium voltage-gated channel subfamily Q member 2
• Synonyms gene
  • EBN
  • EBN1
• Synonyms gene name
  • potassium voltage-gated channel, KQT-like subfamily, member 2
  • potassium channel, voltage gated KQT-like subfamily Q, member 2
• Synonyms
  • Kv7.2
  • ENB1
  • BFNC
  • KCNA11
  • HNSPC
• GenBank acession
  • AF033348
• Locus
  20q13.33
• Discovery year
  1998-01-12
• Entrez gene record
  3785
• Pubmed identfication
  • 9425895
  • 16382104
• RefSeq identity
  • NM_172109
• Classification
  • Potassium voltage-gated channels
• VEGA ID
  OTTHUMG00000033049

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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