(±)-Blebbistatin

• Catalog number
  2405-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (±)-1,​2,​3,​3a-​tetrahydro-​3a-​hydroxy-​6-​methyl-​1-​phenyl-​4H-​pyrrolo[2,​3-​b]quinolin-​4-​one
• Description
  Cell-permeable. A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC₅₀ = 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC₅₀ = 80 μM). Through these effects, blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells.
• CAS Number
  674289-55-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₆N₂O₂
• Molecular Weight
  292.34
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~25 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  A selective non-muscle myosin II ATPases inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD04113775
• PubChem CID
  3476986
• PubChem CID Link
• SMILES
  CC1=CC2=C(C=C1)N=C3C(C2=O)(CCN3C4=CC=CC=C4)O
• InChi
  InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3
• InChi Key
  LZAXPYOBKSJSEX-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Blebbistatin  
• Short name
  (±)-Blebbistatin
• Alternative name
  (±)-Blebbistatin

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