Cancer Cell Stemness Inhibitor I
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Catalog number
2476-5
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Price
Please ask
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Size
5 mg
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Alternative_name
2-Acetylnaphtho[2,3-b]furan-4,9-dione; BBI608
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Description
A potent small molecule anticancer agent that prevents self-renewal in Cancer Stem Cells (CSCs). Also induces cell death in CSCs and non-stem cancer cells.
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CAS Number
83280-65-3
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₁₄H₈O₄
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Molecular Weight
240.21
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO
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Handling
Protect from air and light
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Tag Line
A Cancer Cell Stemness inhibitor
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
24 months
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PubChem CID
10331844
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SMILES
O=C1C2=C(C=C(C(C)=O)O2)C(C3=C1C=CC=C3)=O
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InChi
InChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3
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InChi Key
DPHUWDIXHNQOSY-UHFFFAOYSA-N
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MSDS Available
Yes
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Additional description
For cells, cell lines and tissues in culture till half confluency. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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