TNF Receptor Associated Factor 6 (TRAF6) Polyclonal Antibody
-
Catalog numberCAU22170
-
PricePlease ask
-
Size50 μg
-
-
Other nameRNF85; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer
-
ImmunogenTRAF6 (Gln254~Asn475)
-
Verified reactivityMus musculus (Mouse)
-
Verified applicationsWB, ICC, IHC-P, IHC-F, ELISA
-
Raised inRabbit
-
ClonalityPolyclonal
-
Protein numberPlease see Uniprot
-
Gene numberPlease refer to GenBank
-
NCBI numberPlease refer to NCBI
-
PurityAffinity purified. Please contact us for more details
-
Antibody s concentration200μg/ml
-
Storage recommendationAliquot and store at -20°C. Minimize freezing and thawing.
-
Use before1 year
-
Shipping requirementsBlue ice
-
Estimated production time7-11 business days
-
Supplementary informationApplicable secondary antibody is available. Please inquire
-
NotesFor research use only. Not for diagnostic procedures.
-
PropertiesIf you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
-
French translationanticorps
-
Gene target
-
Gene symbolTNF, TRAF6, TNFRSF1A, TNFRSF1B, LTBR
-
Short nameTNF Receptor Associated Factor 6 (TRAF6) Polyclonal Antibody
-
TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
LabelUnconjugated. Biotin/FITC/Cy3/Cy5 labelling is available, please inquire.
-
Alternative nametumor necrosis factor Receptor Associated Factor 6 (tumor necrosis factor receptor-associated factor 6, E3 ubiquitin protein ligase) polyclonal (antibody to-)
-
Alternative techniquepolyclonals, antibodies
-
Alternative to gene targetTNF receptor-associated factor 6, E3 ubiquitin protein ligase, MGC:3310 and RNF85, TRAF6 and IDBG-40102 and ENSG00000175104 and 7189, protein N-terminus binding, nuclei, Traf6 and IDBG-193222 and ENSMUSG00000027164 and 22034, TRAF6 and IDBG-636763 and ENSBTAG00000036009 and 539124
-
Gene info
-
Identity
-
Gene
-
Long gene nametumor necrosis factor
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameTNF receptor associated factor 6
-
Synonyms gene name
- TNF receptor-associated factor 6, E3 ubiquitin protein ligase
-
Synonyms
-
Locus
-
Discovery year1997-06-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Ring finger proteins
- TNF receptor associated factors
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameTNF receptor superfamily member 1A
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-01-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameTNF receptor superfamily member 1B
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-01-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namelymphotoxin beta receptor
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-03-12
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor receptor superfamily
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data