anti-ZEB2 Antibody

• Catalog number
  5827
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  ZEB2 Antibody: ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues. Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.
• Gene names
  ZEB2 Antibody: SIP1, SIP-1, ZFHX1B, HSPC082, SMADIP1, KIAA0569, SIP1, ZFX1B, HRIHFB2411, Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1
• Antibodie s label
  unlabelled serum
• Purity
  ZEB2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  ZEB2 antibody is predicted to not cross-react with ZEB1.
• Antigen
  ZEB2 antibody was made against an 18 amino acid synthetic peptide near the carboxy terminus of human ZEB2.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
• Antibody advice
  ZEB2 antibody can be used for detection of ZEB2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunocytochemistry starting at 20 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  ZEB2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  ZEB2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  117558786
• Ncbi nr
  AAI27103
• KDa
  Predicted: 134 kDa Observed: Due to post-translational modifications, ZEB2 migrates at ~180 kDa in SDS-PAGE.
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  9839
• GENE symbol
  ZEB2
• Antigene name
  zinc finger E-box binding homeobox 2
• Source
  Homo sapiens
• Protein nr
  O60315
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ZEB2  
• Gene symbol
  ZEB2-AS1, ZEB2
• Short name
  anti-ZEB2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toZEB2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  zinc finger E-box binding homeobox 2, HSPC082 and SIP-1 and SIP1 and SMADIP1 and ZFHX1B, ZEB2 and IDBG-71713 and ENSG00000169554 and 9839, R-SMAD binding, nuclei, Zeb2 and IDBG-168224 and ENSMUSG00000026872 and 24136, BT.99328 and IDBG-642115 and ENSBTAG00000012615 and

Gene info

• Identity
  HGNC:37149
• Gene
  ZEB2-AS1
• Long gene name
  ZEB2 antisense RNA 1
• Synonyms gene
  • ZEB2AS
  • ZEB2-AS
• Synonyms gene name
  • ZEB2 antisense RNA (non-protein coding)
  • ZEB2 antisense RNA 1 (non-protein coding)
• Synonyms
  • ZEB2NAT
• Synonyms name
  • ZEB2 natural antisense transcript
• Locus
  2q22.3
• Discovery year
  2009-08-30
• Entrez gene record
  100303491
• Pubmed identfication
  • 18347095
  • 26152796
• RefSeq identity
  • NR_040248
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000153879

Gene info

• Identity
  HGNC:14881
• Gene
  ZEB2
• Long gene name
  zinc finger E-box binding homeobox 2
• Synonyms gene
  • ZFHX1B
• Synonyms gene name
  • zinc finger homeobox 1b
• Synonyms
  • KIAA0569
  • SIP-1
  • SIP1
• Synonyms name
  • SMAD interacting protein 1
• GenBank acession
  • AB011141
• Locus
  2q22.3
• Discovery year
  2001-03-14
• Entrez gene record
  9839
• RefSeq identity
  • NM_014795
• Classification
  • ZF class homeoboxes and pseudogenes
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000187624

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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