Eotaxin Antibody

• Catalog number
  PB9065
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Eotaxin
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB
• Immunogen
  E.coli-derived mouse Eotaxin recombinant protein (Position: H24-P97). Mouse Eotaxin shares 62% and 97% amino acid (aa) sequences identity with human and rat Eotaxin, respectively.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Eotaxin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Eotaxin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3(CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11 is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor.
• Related articles
  1. Ogilvie, P.; Bardi, G.; Clark-Lewis, I.; Baggiolini, M.; Uguccioni, M. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5. Blood 97: 1920-1924, 2001. 2. Hein, H.; Schluter, C.; Kulke, R.; Christophers, E.; Schroder, J.-M.; Bartels, J. Genomic organization, sequence, and transcriptional regulation of the human eotaxin gene. Biochem. Biophys. Res. Commun. 237: 537-542, 1997.
• Gene Name
  CCL11
• Protein Name
  Eotaxin
• Gene Full Name
  chemokine (C-C motif) ligand 11
• Synonyms
  C-C motif chemokine 11 antibody|CCL 11 antibody|CCL11 antibody|CCL11_HUMAN antibody|chemokine (C-C motif) ligand 11 antibody|Chemokine C C motif ligand 11 antibody|Chemokine CC Motif Ligand 11 antibody|Chemokine ligand 11 antibody|Eosinophil chemotactic protein antibody|Eotaxin antibody|eotaxin-1 antibody|MGC22554 antibody|SCYA 11 antibody|SCYA11 antibody|Small inducible cytokine A11 antibody|Small inducible cytokine subfamily A (Cys Cys) member 11 antibody|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody|Small inducible cytokine subfamily A member 11 antibody|Small-inducible cytokine A11 antibody
• Uniprot ID
  P48298
• Entrez GeneID
  20292
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Eotaxin  
• Gene symbol
  CCL11, CCL24, CCL26
• Short name
  Eotaxin Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Eotaxin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10610
• Gene
  CCL11
• Long gene name
  C-C motif chemokine ligand 11
• Synonyms gene
  • SCYA11
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
  • chemokine (C-C motif) ligand 11
• Synonyms
  • eotaxin
  • MGC22554
• Synonyms name
  • eotaxin-1
• GenBank acession
  • AB063614
• Locus
  17q12
• Discovery year
  1996-04-24
• Entrez gene record
  6356
• Pubmed identfication
  • 9169149
• RefSeq identity
  • NM_002986
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132884

Gene info

• Identity
  HGNC:10623
• Gene
  CCL24
• Long gene name
  C-C motif chemokine ligand 24
• Synonyms gene
  • SCYA24
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 24
  • chemokine (C-C motif) ligand 24
• Synonyms
  • Ckb-6
  • MPIF-2
  • eotaxin-2
  • MPIF2
• Synonyms name
  • CK-beta-6
  • myeloid progenitor inhibitory factor 2
  • eotaxin-2
• GenBank acession
  • U85768
• Locus
  7q11.23
• Discovery year
  1997-11-14
• Entrez gene record
  6369
• Pubmed identfication
  • 9104803
  • 9598329
• RefSeq identity
  • NM_002991
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000156635

Gene info

• Identity
  HGNC:10625
• Gene
  CCL26
• Long gene name
  C-C motif chemokine ligand 26
• Synonyms gene
  • SCYA26
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 26
  • chemokine (C-C motif) ligand 26
• Synonyms
  • MIP-4alpha
  • eotaxin-3
  • IMAC
  • MIP-4a
  • TSC-1
• Synonyms name
  • macrophage inflammatory protein 4-alpha
  • small inducible cytokine A26
  • CC chemokine IMAC
  • chemokine N1
  • thymic stroma chemokine-1
  • eotaxin-3
• GenBank acession
  • AF124601
• Locus
  7q11.23
• Discovery year
  1999-06-09
• Entrez gene record
  10344
• Pubmed identfication
  • 10373330
• RefSeq identity
  • NM_006072
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000130403

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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