Optovin

  • Catalog number
    9594-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone
  • Description
    Optovin is a reversible photoactive TRPA1 activator. It specifically activates TRPA1 (EC₅₀ = 2 μM) but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals.
  • CAS Number
    348575-88-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₁₃N₃OS₂
  • Molecular Weight
    315.41
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>30 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A reversible photoactive TRPA1 activator
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    1365101
  • SMILES
    CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)NC(=S)S3
  • InChi
    InChI=1S/C15H13N3OS2/c1-9-6-11(7-13-14(19)17-15(20)21-13)10(2)18(9)12-4-3-5-16-8-12/h3-8H,1-2H3,(H,17,19,20)/b13-7+
  • InChi Key
    YISGMOZSGOGYOU-NTUHNPAUSA-N
  • MSDS Available
    Yes
  • Gene target
    Optovin  
  • Short name
    Optovin
  • Alternative name
    Optovin
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