Optovin
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Catalog number9594-5
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PricePlease ask
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Size5 mg
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Alternative_name5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone
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DescriptionOptovin is a reversible photoactive TRPA1 activator. It specifically activates TRPA1 (EC₅₀ = 2 μM) but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals.
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CAS Number348575-88-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₁₃N₃OS₂
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Molecular Weight315.41
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>30 mg/ml)
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HandlingProtect from air and light
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Tag LineA reversible photoactive TRPA1 activator
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID1365101
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SMILESCC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)NC(=S)S3
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InChiInChI=1S/C15H13N3OS2/c1-9-6-11(7-13-14(19)17-15(20)21-13)10(2)18(9)12-4-3-5-16-8-12/h3-8H,1-2H3,(H,17,19,20)/b13-7+
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InChi KeyYISGMOZSGOGYOU-NTUHNPAUSA-N
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MSDS AvailableYes
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Gene target
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Short nameOptovin
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Alternative nameOptovin
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