AVL-292 (Spebrutinib)

• Catalog number
  9413-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide; CC-292
• Description
  AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK) (IC₅₀ = 0. 5 nM) with potential antineoplastic activity.
• CAS Number
  1202757-89-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₂FN₅O₃
• Molecular Weight
  423.44
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  59174488
• PubChem CID Link
• SMILES
  COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F
• InChi
  InChI=1S/C22H22FN5O3/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28)
• InChi Key
  KXBDTLQSDKGAEB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AVL-292   Spebrutinib  
• Short name
  AVL-292 (Spebrutinib)
• Alternative name
  AVL-292 (Spebrutinib)

Similar products