Recombinant Human Uracil Phosphoribosyltransferase Homolog/UPRT Protein(N-6His)

• Catalog number
  PKSH033196-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Uracil phosphoribosyltransferase homolog; UPP; FUR1; UPRT
• Activity
  NA
• Sequence
  Met1-Asp309
• Fusion tag
  N-6His
• Accession
  Q96BW1
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  35.9 kDa
• AP Mol Mass
  40 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl pH 8.0.
• Background
  UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Uracil   Phosphoribosyltransferase   Homolog/UPRT   Protein   N-6His  
• Gene symbol
  UPRT
• Short name
  Recombinant Uracil Phosphoribosyltransferase Homolog/UPRT Protein(N-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Uracil Phosphoribosyltransferase Homolog/UPRT Protein(N-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:28334
• Gene
  UPRT
• Long gene name
  uracil phosphoribosyltransferase homolog
• Synonyms gene name
  • uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
• Synonyms
  • DKFZp781E1243
  • MGC23937
  • FUR1
  • RP11-311P8.3
• GenBank acession
  • BC015116
• Locus
  Xq13.3
• Discovery year
  2006-12-07
• Entrez gene record
  139596
• Pubmed identfication
  • 26271729
• RefSeq identity
  • NM_145052
• VEGA ID
  OTTHUMG00000021864
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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