BCL2L1 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-1336R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  BCL2L1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-BCL2L1 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BCL2L1
• Specificity
  This is a highly specific antibody against BCL2L1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  70-120/233
• Subcellular location
  Helical
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BCL2L1
• Gene ID Number
  598
• Swiss Prot
  Q07817
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F() activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  BCLX; BCL2L; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; PPP1R52; BCL-XL/S; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; BCL2L1
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-BCL2L1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  BCL2L1  
• Gene symbol
  BCL2L1-AS1, BCL2L1
• Short name
  Anti-BCL2L1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  BCL2L1 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-like 1, Bcl-X and bcl-xL and BCL-XL/S and bcl-xS and BCL2L and BCLX and BCLXL and BCLXS and PPP1R52, BCL2L1 and IDBG-63673 and ENSG00000171552 and 598, BH3 domain binding, nuclei, Bcl2l1 and IDBG-209867 and ENSMUSG00000007659 and 12048, BCL2L1 and IDBG-641541 and ENSBTAG00000006526 and 282152

Gene info

• Identity
  HGNC:40095
• Gene
  BCL2L1-AS1
• Long gene name
  BCL2L1 antisense RNA 1
• Locus
  20q11.21
• Discovery year
  2019-07-24
• Entrez gene record
  105372589
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:992
• Gene
  BCL2L1
• Long gene name
  BCL2 like 1
• Synonyms
  • BCLX
  • BCL2L
  • Bcl-X
  • bcl-xL
  • bcl-xS
  • PPP1R52
• Synonyms name
  • protein phosphatase 1, regulatory subunit 52
• GenBank acession
  • Z23115
• Locus
  20q11.21
• Discovery year
  1997-10-30
• Entrez gene record
  598
• Pubmed identfication
  • 8358789
• RefSeq identity
  • NM_138578
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000032192

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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