anti- SIRT1 antibody
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Catalog numberFNab07877
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PricePlease ask
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Size2X100μg
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Formliquid
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PurificationImmunogen affinity purified
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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BackgroundThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
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Immunogensirtuin (silent mating type information regulation 2 homolog) 1
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SynonymsSIR2L1
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Calculated MW130 kDa
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Uniprot IDQ96EB6
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SpecificityHuman, Mouse, Rat
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Tested ApplicationELISA, WB, IHC, IP
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Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100
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Image1Immunohistochemistry of paraffin-embedded mouse testis tissue slide using FNab07877( SIRT1 Antibody) at dilution of 1:100
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Image4HeLa cells were subjected to SDS PAGE followed by western blot with FNab07877( SIRT1 Antibody) at dilution of 1:1000
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSIRT1-AS, SIRT1
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Short nameanti- SIRT1 antibody
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit
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IsotypeIgG
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Alternative nameantibody to- sirtuin 1 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetsirtuin 1, SIR2L1, SIRT1 and IDBG-75847 and ENSG00000096717 and 23411, keratin filament binding, nuclei, Sirt1 and IDBG-159441 and ENSMUSG00000020063 and 93759, SIRT1 and IDBG-629119 and ENSBTAG00000014023 and 613629
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Gene info
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Identity
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Gene
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Long gene nameSIRT1 antisense RNA
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Locus
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Discovery year2015-09-23
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Entrez gene record
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Pubmed identfication
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene namesirtuin 1
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Synonyms gene name
- sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1
- sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-03-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- eNoSC complex
- Sirtuins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data