CD44 / Pgp-1 monoclonal antibody

• Catalog number
  1F-341-T025
• Price
  Please ask
• Size
  25 assays

• Long name
  Mouse Monoclonal Antibody against Human CD44 / Pgp-1, Clone: MEM-263
• Antigen
  CD44
• Species reactivity
  Human (Homo sapiens), Porcine, Canine (Dog)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-263
• Applications
  FC, IP, WB, IHC(P)
• Immunogen
  COS-7 cells (African Green Monkey).
• Format conjugation
  FITC
• Specificity
  The antibody MEM-263 reacts with extracellular (N-terminal) domain of standard CD44 (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes._x000D_ HLDA III; WS Code T 155
• Research area
  CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD44 / Pgp-1, Clone: MEM-263 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  *Leukocyte Typing III., McMichael A.J. et al. (Eds.), Oxford University Press (1987).
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD44   Pgp-1   monoclonal  
• Gene symbol
  CD44-AS1, CD44
• Short name
  Anti-CD44 / Pgp-1 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD44 / Pgp-1
• Alternative technique
  antibodies
• Alternative to gene target
  CD44 molecule (Indian blood group), CDW44 and CSPG8 and ECMR-III and HCELL and HUTCH-I and IN and LHR and MC56 and MDU2 and MDU3 and MIC4 and Pgp1, CD44 and IDBG-39556 and ENSG00000026508 and 960, hyaluronic acid binding, Cell surfaces, Cd44 and IDBG-193505 and ENSMUSG00000005087 and 12505, CD44 and IDBG-636564 and ENSBTAG00000011578 and 281057

Gene info

• Identity
  HGNC:40133
• Gene
  CD44-AS1
• Long gene name
  CD44 antisense RNA 1
• Synonyms
  • RP1-68D18.4
• Locus
  11p13
• Discovery year
  2017-02-10
• Pubmed identfication
  • 28103885
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:1681
• Gene
  CD44
• Long gene name
  CD44 molecule (Indian blood group)
• Synonyms gene
  • MIC4
  • MDU2
  • MDU3
• Synonyms gene name
  • CD44 antigen (homing function and Indian blood group system)
• Synonyms
  • IN
  • MC56
  • Pgp1
  • CD44R
  • HCELL
  • CSPG8
• Synonyms name
  • hematopoietic cell E- and L-selectin ligand
  • chondroitin sulfate proteoglycan 8
• GenBank acession
  • M59040
• Locus
  11p13
• Discovery year
  1989-06-30
• Entrez gene record
  960
• Pubmed identfication
  • 2454887
• RefSeq identity
  • NM_000610
• Classification
  • Proteoglycans
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000044388
• Locus Specific Databases
  • LRG_815

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