Ferrostatin-1
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Catalog number2230-25
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PricePlease ask
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Size25 mg
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Alternative_nameFer-1; Ethyl 3-amino-4-(cyclohexylamino)benzoate
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DescriptionCell-permeable. A potent ferroptosis (an iron-dependent form of non-apoptotic cell death) inhibitor. Inhibits erastin-induced ferroptosis in HT-1080 cells with an EC₅₀ of 60 nM. Ferrostatin-1 inhibits ferroptosis in cancer cells as well as blocks glutamate-induced cell death in organotypic rat brain slices.
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CAS Number347174-05-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₂₂N₂O₂
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Molecular Weight262.35
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Cell PermeableYes
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Purity≥95% by HPLC
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SolubilitiesDMSO (100 mM)
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HandlingProtect from light and moisture
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Tag LineA ferroptosis inhibitor.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD08072959
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PubChem CID4068248
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SMILESCCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N
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InChiInChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3
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InChi KeyUJHBVMHOBZBWMX-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameFerrostatin-1
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Alternative nameFerrostatin-1
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