Andrographolide

  • Catalog number
    2389-250
  • Price
    Please ask
  • Size
    250 mg
  • Description
    A major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-apoptotic, anti-viral and anti-proliferative effects in vitro and in vivo. Prevents hyperglycemia in rat diabetes model. Irreversible antagonist of NK-κB and AP-1 (IC₅₀ = 15 µM).
  • CAS Number
    5508-58-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₀H₃₀O₆
  • Molecular Weight
    350.45
  • Cell Permeable
    Yes
  • Purity
    ≥98% by NMR
  • Solubilities
    DMSO (~25 mg/ml) or EtOH (~ 8 mg/ml)
  • Handling
    Protect from light and air
  • Tag Line
    A NF-kappa B activation inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD07778082
  • PubChem CID
    5318517
  • SMILES
    CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O
  • InChi
    InChI=1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1
  • InChi Key
    BOJKULTULYSRAS-OTESTREVSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Andrographolide
  • Alternative name
    Andrographolide
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