Recombinant Human NCF-2 / NCF2 / P67phox Protein (His & GST tag)

  • Catalog number
    PKSH030528-20µg
  • Price
    Please ask
  • Size
    20µg
  • Synonym
    NCF-2;NOXA2;P67-PHOX;P67PHOX
  • Activity
    NA
  • Sequence
    Met1-Val526
  • Fusion tag
    N-His & GST
  • Accession
    AAH01606.1
  • Expressed Host
    Baculovirus-Insect Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >90 % as determined by SDS-PAGE
  • Endotoxin
    <1.0 EU per µg as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    87.6 kDa
  • AP Mol Mass
    80-90 kDa
  • Formulation
    Lyophilized from sterile 20mM Tris, 500mM Nacl, 10% glycerol, pH 7.4
  • Background
    NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.
  • Conjugation
    histidine
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    NCF-2   NCF2   P67phox   Protein   His   GST   tag  
  • Gene symbol
    NCF2, MGST3, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2, RNU6-2, KRTAP13-2
  • Short name
    Recombinant NCF-2 / NCF2 / P67phox Protein (His & GST tag)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    His
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens NCF-2 / neutrophil cytosolic factor 2 / P67phox Protein (histidine & GST detection labelled)
  • Alternative technique
    rec
  • Alternative to gene target
    neutrophil cytosolic factor 2, NCF-2 and NOXA2 and P67-PHOX and P67PHOX, NCF2 and IDBG-105312 and ENSG00000116701 and 4688, Rac GTPase binding, nuclei, Ncf2 and IDBG-198618 and ENSMUSG00000026480 and 17970, NCF2 and IDBG-637262 and ENSBTAG00000008004 and 281346
Gene info
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MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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