anti- CD3 epsilon antibody
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Catalog number
FNab01458
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Price
Please ask
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Size
2X100μg
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Form
liquid
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Purification
Immunogen affinity purified
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Purity
≥95% as determined by SDS-PAGE
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Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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Background
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
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Immunogen
CD3e molecule, epsilon (CD3-TCR complex)
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Calculated MW
23 kDa
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Uniprot ID
P07766
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Specificity
Human, Mouse, Rat
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Tested Application
ELISA, WB, IHC
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Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
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Image1
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01458( CD3E Antibody) at dilution of 1:200 Heat mediated antigen retrieved with Tris-EDTA buffer, pH9.0
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Image4
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01458(CD3E antibody) at dilution of 1:1000
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
CD3E, POLR1G
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Short name
anti- CD3 epsilon antibody
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Technique
Antibody, anti, antibody to, antibodies against human proteins, antibodies for
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Host
Rabbit
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Isotype
IgG
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Alternative name
antibody to- CD3 epsilon (antibody to-)
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
CD3e molecule
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Synonyms gene name
- CD3e antigen, epsilon polypeptide (TiT3 complex)
- CD3e molecule, epsilon (CD3-TCR complex)
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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